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Synphilin-1 attenuates mutant LRRK2-induced neurodegeneration in Parkinson's disease models
Mutations in leucine-rich repeat kinase 2 (LRRK2) cause autosomal-dominant Parkinsonism with pleomorphic pathology including deposits of aggregated protein and neuronal degeneration. The pathogenesis of LRRK2-linked Parkinson's disease (PD) is not fully understood. Here, using co-immunoprecipit...
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| Udgivet i: | Hum Mol Genet |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4743687/ https://ncbi.nlm.nih.gov/pubmed/26744328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv504 |
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