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Mitochondrial disease genes COA6, COX6B and SCO2 have overlapping roles in COX2 biogenesis

Biogenesis of cytochrome c oxidase (CcO), the terminal enzyme of the mitochondrial respiratory chain, is a complex process facilitated by several assembly factors. Pathogenic mutations were recently reported in one such assembly factor, COA6, and our previous work linked Coa6 function to mitochondri...

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Publicat a:Hum Mol Genet
Autors principals: Ghosh, Alok, Pratt, Anthony T., Soma, Shivatheja, Theriault, Sarah G., Griffin, Aaron T., Trivedi, Prachi P., Gohil, Vishal M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743686/
https://ncbi.nlm.nih.gov/pubmed/26669719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv503
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