Copper supplementation restores cytochrome c oxidase assembly defect in a mitochondrial disease model of COA6 deficiency

Mitochondrial respiratory chain biogenesis is orchestrated by hundreds of assembly factors, many of which are yet to be discovered. Using an integrative approach based on clues from evolutionary history, protein localization and human genetics, we have identified a conserved mitochondrial protein, C...

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Huvudupphovsmän: Ghosh, Alok, Trivedi, Prachi P., Timbalia, Shrishiv A., Griffin, Aaron T., Rahn, Jennifer J., Chan, Sherine S. L., Gohil, Vishal M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049311/
https://ncbi.nlm.nih.gov/pubmed/24549041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu069
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