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Holocarboxylase synthetase interacts physically with nuclear receptor co-repressor, histone deacetylase 1 and a novel splicing variant of histone deacetylase 1 to repress repeats
HLCS (holocarboxylase synthetase) is a nuclear protein that catalyses the binding of biotin to distinct lysine residues in chromatin proteins. HLCS-dependent epigenetic marks are overrepresented in repressed genomic loci, particularly in repeats. Evidence is mounting that HLCS is a member of a multi...
Gardado en:
| Publicado en: | Biochem J |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4743672/ https://ncbi.nlm.nih.gov/pubmed/24840043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20131208 |
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