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Holocarboxylase synthetase interacts physically with nuclear receptor co-repressor, histone deacetylase 1 and a novel splicing variant of histone deacetylase 1 to repress repeats

HLCS (holocarboxylase synthetase) is a nuclear protein that catalyses the binding of biotin to distinct lysine residues in chromatin proteins. HLCS-dependent epigenetic marks are overrepresented in repressed genomic loci, particularly in repeats. Evidence is mounting that HLCS is a member of a multi...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biochem J
Egile Nagusiak: Liu, Dandan, Zempleni, Janos
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743672/
https://ncbi.nlm.nih.gov/pubmed/24840043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20131208
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