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Comparison of KRAS mutation analysis of colorectal cancer samples by standard testing and next-generation sequencing

AIMS: Based on KRAS testing, the subset of patients with metastatic colorectal cancer (CRC) that could benefit from anti-EGFR therapy can be better delineated. Though KRAS testing has become significantly more prevalent over the last few years, methods for testing remain heterogeneous and discordanc...

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Veröffentlicht in:J Clin Pathol
Hauptverfasser: Kothari, Nishi, Schell, Michael J, Teer, Jamie K, Yeatman, Timothy, Shibata, David, Kim, Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743643/
https://ncbi.nlm.nih.gov/pubmed/25004944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jclinpath-2014-202405
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