Intracellular mGluR5 plays a critical role in neuropathic pain

Spinal mGluR5 is a key mediator of neuroplasticity underlying persistent pain. Although brain mGluR5 is localized on cell surface and intracellular membranes, neither the presence nor physiological role of spinal intracellular mGluR5 is established. Here we show that in spinal dorsal horn neurons &g...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Vincent, Kathleen, Cornea, Virginia M., Jong, Yuh-Jiin I., Laferrière, André, Kumar, Naresh, Mickeviciute, Aiste, Fung, Jollee S. T., Bandegi, Pouya, Ribeiro-da-Silva, Alfredo, O'Malley, Karen L., Coderre, Terence J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742982/
https://ncbi.nlm.nih.gov/pubmed/26837579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10604
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