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Ryanodine Receptor Sensitization Results in Abnormal Calcium Signaling in Airway Smooth Muscle Cells

Intracellular Ca(2+) dynamics of airway smooth muscle cells (ASMCs) are believed to play a major role in airway hyperresponsiveness and remodeling in asthma. Prior studies have underscored a prominent role for inositol 1,4,5-triphosphate (IP(3)) receptors in normal agonist-induced Ca(2+) oscillation...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Croisier, Huguette, Tan, Xiahui, Chen, Jun, Sneyd, James, Sanderson, Michael J., Brook, Bindi S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742950/
https://ncbi.nlm.nih.gov/pubmed/25874477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0386OC
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