Ryanodine Receptor Sensitization Results in Abnormal Calcium Signaling in Airway Smooth Muscle Cells

Intracellular Ca(2+) dynamics of airway smooth muscle cells (ASMCs) are believed to play a major role in airway hyperresponsiveness and remodeling in asthma. Prior studies have underscored a prominent role for inositol 1,4,5-triphosphate (IP(3)) receptors in normal agonist-induced Ca(2+) oscillation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Respir Cell Mol Biol
Prif Awduron: Croisier, Huguette, Tan, Xiahui, Chen, Jun, Sneyd, James, Sanderson, Michael J., Brook, Bindi S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2015
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742950/
https://ncbi.nlm.nih.gov/pubmed/25874477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0386OC
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