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Bitter tasting compounds dilate airways by inhibiting airway smooth muscle calcium oscillations and calcium sensitivity
BACKGROUND AND PURPOSE: While selective, bitter tasting, TAS2R agonists can relax agonist-contracted airway smooth muscle (ASM), their mechanism of action is unclear. However, ASM contraction is regulated by Ca(2+) signalling and Ca(2+) sensitivity. We have therefore investigated how the TAS2R10 ago...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
British Journal of Pharmacology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3969078/ https://ncbi.nlm.nih.gov/pubmed/24117140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12460 |
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