Chimeric tumor necrosis factor-TrkA receptors reveal that ligand-dependent activation of the TrkA tyrosine kinase is sufficient for differentiation and survival of PC12 cells.

To elucidate the function of the two nerve growth factor (NGF) receptors, p75NGFR and p140trk, chimeric molecules were constructed of tumor necrosis factor (TNF) and NGF receptors. Rat PC12 pheochromocytoma cells transiently transfected with TNF-p140trk chimeras, which contain the extracellular doma...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Rovelli, G, Heller, R A, Canossa, M, Shooter, E M
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC47429/
https://ncbi.nlm.nih.gov/pubmed/7690970
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items