The Prodomain-bound Form of Bone Morphogenetic Protein 10 Is Biologically Active on Endothelial Cells

BMP10 is highly expressed in the developing heart and plays essential roles in cardiogenesis. BMP10 deletion in mice results in embryonic lethality because of impaired cardiac development. In adults, BMP10 expression is restricted to the right atrium, though ventricular hypertrophy is accompanied by...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Jiang, He, Salmon, Richard M., Upton, Paul D., Wei, Zhenquan, Lawera, Aleksandra, Davenport, Anthony P., Morrell, Nicholas W., Li, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742757/
https://ncbi.nlm.nih.gov/pubmed/26631724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.683292
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