Reactive Center Loop (RCL) Peptides Derived from Serpins Display Independent Coagulation and Immune Modulating Activities

Serpins regulate coagulation and inflammation, binding serine proteases in suicide-inhibitory complexes. Target proteases cleave the serpin reactive center loop scissile P1–P1′ bond, resulting in serpin-protease suicide-inhibitory complexes. This inhibition requires a near full-length serpin sequenc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Ambadapadi, Sriram, Munuswamy-Ramanujam, Ganesh, Zheng, Donghang, Sullivan, Colin, Dai, Erbin, Morshed, Sufi, McFadden, Baron, Feldman, Emily, Pinard, Melissa, McKenna, Robert, Tibbetts, Scott, Lucas, Alexandra
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2016
Gaiak:
Immunology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742751/
https://ncbi.nlm.nih.gov/pubmed/26620556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.704841
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak