Extracellular Fibrinogen-binding Protein (Efb) from Staphylococcus aureus Inhibits the Formation of Platelet-Leukocyte Complexes

Extracellular fibrinogen-binding protein (Efb) from Staphylococcus aureus inhibits platelet activation, although its mechanism of action has not been established. In this study, we discovered that the N-terminal region of Efb (Efb-N) promotes platelet binding of fibrinogen and that Efb-N binding to...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Posner, Mareike G., Upadhyay, Abhishek, Abubaker, Aisha Alsheikh, Fortunato, Tiago M., Vara, Dina, Canobbio, Ilaria, Bagby, Stefan, Pula, Giordano
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742742/
https://ncbi.nlm.nih.gov/pubmed/26627825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.678359
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