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Coagulase and Efb of Staphylococcus aureus Have a Common Fibrinogen Binding Motif

Coagulase (Coa) and Efb, secreted Staphylococcus aureus proteins, are important virulence factors in staphylococcal infections. Coa interacts with fibrinogen (Fg) and induces the formation of fibrin(ogen) clots through activation of prothrombin. Efb attracts Fg to the bacterial surface and forms a s...

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Bibliografiska uppgifter
I publikationen:mBio
Huvudupphovsmän: Ko, Ya-Ping, Kang, Mingsong, Ganesh, Vannakambadi K., Ravirajan, Dharmanand, Li, Bin, Höök, Magnus
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Microbiology 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725008/
https://ncbi.nlm.nih.gov/pubmed/26733070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01885-15
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