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Coagulase and Efb of Staphylococcus aureus Have a Common Fibrinogen Binding Motif

Coagulase (Coa) and Efb, secreted Staphylococcus aureus proteins, are important virulence factors in staphylococcal infections. Coa interacts with fibrinogen (Fg) and induces the formation of fibrin(ogen) clots through activation of prothrombin. Efb attracts Fg to the bacterial surface and forms a s...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Ko, Ya-Ping, Kang, Mingsong, Ganesh, Vannakambadi K., Ravirajan, Dharmanand, Li, Bin, Höök, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725008/
https://ncbi.nlm.nih.gov/pubmed/26733070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01885-15
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