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Coagulase and Efb of Staphylococcus aureus Have a Common Fibrinogen Binding Motif

Coagulase (Coa) and Efb, secreted Staphylococcus aureus proteins, are important virulence factors in staphylococcal infections. Coa interacts with fibrinogen (Fg) and induces the formation of fibrin(ogen) clots through activation of prothrombin. Efb attracts Fg to the bacterial surface and forms a s...

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Bibliografische gegevens
Gepubliceerd in:mBio
Hoofdauteurs: Ko, Ya-Ping, Kang, Mingsong, Ganesh, Vannakambadi K., Ravirajan, Dharmanand, Li, Bin, Höök, Magnus
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Microbiology 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725008/
https://ncbi.nlm.nih.gov/pubmed/26733070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01885-15
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