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Coagulase and Efb of Staphylococcus aureus Have a Common Fibrinogen Binding Motif

Coagulase (Coa) and Efb, secreted Staphylococcus aureus proteins, are important virulence factors in staphylococcal infections. Coa interacts with fibrinogen (Fg) and induces the formation of fibrin(ogen) clots through activation of prothrombin. Efb attracts Fg to the bacterial surface and forms a s...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Ko, Ya-Ping, Kang, Mingsong, Ganesh, Vannakambadi K., Ravirajan, Dharmanand, Li, Bin, Höök, Magnus
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Microbiology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725008/
https://ncbi.nlm.nih.gov/pubmed/26733070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01885-15
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