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Coagulase and Efb of Staphylococcus aureus Have a Common Fibrinogen Binding Motif

Coagulase (Coa) and Efb, secreted Staphylococcus aureus proteins, are important virulence factors in staphylococcal infections. Coa interacts with fibrinogen (Fg) and induces the formation of fibrin(ogen) clots through activation of prothrombin. Efb attracts Fg to the bacterial surface and forms a s...

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Dettagli Bibliografici
Pubblicato in:mBio
Autori principali: Ko, Ya-Ping, Kang, Mingsong, Ganesh, Vannakambadi K., Ravirajan, Dharmanand, Li, Bin, Höök, Magnus
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Microbiology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725008/
https://ncbi.nlm.nih.gov/pubmed/26733070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01885-15
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