Amyloid Peptide β1-42 Induces Integrin αIIbβ3 Activation, Platelet Adhesion, and Thrombus Formation in a NADPH Oxidase-Dependent Manner

The progression of Alzheimer's dementia is associated with neurovasculature impairment, which includes inflammation, microthromboses, and reduced cerebral blood flow. Here, we investigate the effects of β amyloid peptides on the function of platelets, the cells driving haemostasis. Amyloid pept...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Abubaker, Aisha Alsheikh, Vara, Dina, Visconte, Caterina, Eggleston, Ian, Torti, Mauro, Canobbio, Ilaria, Pula, Giordano
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441506/
https://ncbi.nlm.nih.gov/pubmed/31007831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1050476
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