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Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin
The membrane-anchored serine prostasin (CAP1/PRSS8) is essential for barrier acquisition of the interfollicular epidermis and for normal hair follicle development. Consequently, prostasin null mice die shortly after birth. Prostasin is found in two forms in the epidermis: a one-chain zymogen and a t...
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| Publicat a: | J Biol Chem |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4742728/ https://ncbi.nlm.nih.gov/pubmed/26719335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C115.706721 |
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