Etoposide enhances antitumor efficacy of MDR1-driven oncolytic adenovirus through autoupregulation of the MDR1 promoter activity

Conditionally replicating adenoviruses (CRAds), or oncolytic adenoviruses, such as E1B55K-deleted adenovirus, are attractive anticancer agents. However, the therapeutic efficacy of E1B55K-deleted adenovirus for refractory solid tumors has been limited. Environmental stress conditions may induce nucl...

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Vydáno v:Oncotarget
Hlavní autoři: Su, Bing-Hua, Shieh, Gia-Shing, Tseng, Yau-Lin, Shiau, Ai-Li, Wu, Chao-Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742001/
https://ncbi.nlm.nih.gov/pubmed/26515462
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