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Inhibiting bladder tumor growth with a cell penetrating R11 peptide derived from the p53 C-terminus

Urothelial carcinoma of the bladder (UCB) is the most common malignancy of the urinary tract, nearly half of which contains a mutation in TP53 gene. Hence, therapeutic approach by restoring functional p53 protein in cancer cells will be beneficial. Recent studies have demonstrated the inhibition of...

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Publicat a:Oncotarget
Autors principals: Zhang, Tingting, Wu, Kaijie, Ding, Chen, Sun, Kangwei, Guan, Zhenfeng, Wang, Xinyang, Hsieh, Jer-Tsong, He, Dalin, Fan, Jinhai
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741965/
https://ncbi.nlm.nih.gov/pubmed/26462022
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