Activation of sirtuin 1/3 improves vascular hyporeactivity in severe hemorrhagic shock by alleviation of mitochondrial damage

Vascular hyporeactivity is one of the major causes responsible for refractory hypotension and associated mortality in severe hemorrhagic shock. Mitochondrial permeability transition (mPT) pore opening in arteriolar smooth muscle cells (ASMCs) is involved in the pathogenesis of vascular hyporeactivit...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Li, Pengyun, Meng, Xianzhong, Bian, Huining, Burns, Nana, Zhao, Ke-seng, Song, Rui
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2015
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Research Paper: Pathology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741911/
https://ncbi.nlm.nih.gov/pubmed/26473372
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