Transfected human liver cytochrome P-450 hydroxylates vitamin D analogs at different side-chain positions.
A full-length cDNA for the human liver mitochondrial cytochrome P-450 CYP27 was cloned from a human hepatoma HepG2 cDNA library and then subcloned into the mammalian expression vector pSG5. When CYP27 cDNA was transfected into COS-1 transformed monkey kidney cells along with adrenodoxin cDNA, transf...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1993
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47419/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7690968/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.18.8668 |
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