Engineering a cytochrome P450 enzyme as a peroxygenase for selective hydroxylation of steroids
Abstract Selective activation of steroid skeletons is crucial for the generation of pharmaceutically valuable compounds. Despite the success of engineering cytochrome P450 enzymes as peroxygenases to utilize cost-effective H2O2, their applications are limited due to poor H2O2 tolerance. Here, we rep...
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| Автори: | , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Nature Portfolio
2026-02-01
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| Серія: | Nature Communications |
| Онлайн доступ: | https://doi.org/10.1038/s41467-026-69211-8 |
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