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Frizzled-7 promoter is highly active in tumors and promoter-driven Shiga-like toxin I inhibits hepatocellular carcinoma growth

Frizzled-7 protein plays a significant role in the formation of several malignant tumors. Up regulation of the Frizzled-7 in cancer cell lines is associated with nuclear accumulation of wild-type β-catenin from the Wnt/β-catenin pathway which is frequently activated in tumors. To analyze activity of...

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Publicat a:Oncotarget
Autors principals: Xu, Hongpan, Gong, Lailing, Xia, Yanyan, Qu, Lili, Li, Qiwen, Pang, Lu, Si, Jin, Li, Zhiyang
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741869/
https://ncbi.nlm.nih.gov/pubmed/26498690
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