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Shiga‐like toxin I exerts specific and potent anti‐tumour efficacy against gastric cancer cell proliferation when driven by tumour‐preferential Frizzled‐7 promoter

OBJECTIVES: Tumour‐targeted gene therapy is a promising approach for effective control of gastric cancer cell proliferation. Our study aims to develop a cancer therapy which combines tumour‐targeting promoters with cytotoxins. METHODS: The expression of globotriaosylceramide (Gb3), which is a Shiga‐...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Xu, Hongpan, Peng, Lijun, Shen, Mengjiao, Xia, Yanyan, Li, Zhiyang, He, Nongyue
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536451/
https://ncbi.nlm.nih.gov/pubmed/30955216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12607
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