Novel agents for advanced pancreatic cancer

Pancreatic cancer is relatively insensitive to conventional chemotherapy. Therefore, novel agents targeting dysregulated pathways (MAPK/ERK, EGFR, TGF-β, HEDGEHOG, NOTCH, IGF, PARP, PI3K/AKT, RAS, and Src) are being explored in clinical trials as monotherapy or in combination with cytotoxic chemothe...

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Foilsithe in:Oncotarget
Main Authors: Akinleye, Akintunde, Iragavarapu, Chaitanya, Furqan, Muhammad, Cang, Shundong, Liu, Delong
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2015
Ábhair:
Review
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741843/
https://ncbi.nlm.nih.gov/pubmed/26369833
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