Novel ALK inhibitors in clinical use and development

Anaplastic lymphoma kinase 1 (ALK-1) is a member of the insulin receptor tyrosine kinase family. ALK-1 was initially found in anaplastic large cell lymphoma (ALCL). ALK mutations have also been implicated in the pathogenesis of non-small cell lung cancer (NSCLC) and other solid tumors. Multiple smal...

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Bibliographic Details
Published in:J Hematol Oncol
Main Authors: Iragavarapu, Chaitanya, Mustafa, Milaim, Akinleye, Akintunde, Furqan, Muhammad, Mittal, Varun, Cang, Shundong, Liu, Delong
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349797/
https://ncbi.nlm.nih.gov/pubmed/25888090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0122-8
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