The metastasis suppressor, NDRG1, inhibits “stemness” of colorectal cancer via down-regulation of nuclear β-catenin and CD44

N-myc downstream-regulated gene 1 (NDRG1), has been identified as an important metastasis suppressor for colorectal cancer (CRC). In this study, we investigated: (1) the effects of NDRG1 on CRC stemness and tumorigenesis; (2) the molecular mechanisms involved; and (3) the relationship between NDRG1...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wangpu, Xiongzhi, Yang, Xiao, Zhao, Jingkun, Lu, Jiaoyang, Guan, Shaopei, Lu, Jun, Kovacevic, Zaklina, Liu, Wensheng, Mi, Lan, Jin, Runsen, Sun, Jing, Yue, Fei, Ma, Junjun, Lu, Aiguo, Richardson, Des R., Wang, Lishun, Zheng, Minhua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741810/
https://ncbi.nlm.nih.gov/pubmed/26418878
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