Liver X receptor reduces proliferation of human oral cancer cells by promoting cholesterol efflux via up-regulation of ABCA1 expression

Liver X receptors (LXRs) contribute not only to maintain cholesterol homeostasis but also to control cell growth. However, the molecular mechanisms behind the LXR-mediated anti-proliferative effects are largely unknown. Here we show, by immunohistochemistry, that LXRα and LXRβ are differentially dis...

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Udgivet i:Oncotarget
Main Authors: Kaneko, Tetsuharu, Kanno, Chihiro, Ichikawa-Tomikawa, Naoki, Kashiwagi, Korehito, Yaginuma, Nanae, Ohkoshi, Chihiro, Tanaka, Mizuko, Sugino, Takashi, Imura, Tetsuya, Hasegawa, Hiroshi, Chiba, Hideki
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741770/
https://ncbi.nlm.nih.gov/pubmed/26452260
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