Immature myeloid progenitors promote disease progression in a mouse model of Barrett's-like metaplasia

Cdx2, an intestine specific transcription factor, is expressed in Barrett's esophagus (BE). We sought to determine if esophageal Cdx2 expression would accelerate the onset of metaplasia in the L2-IL-1β transgenic mouse model for Barrett's-like metaplasia. The K14-Cdx2::L2-IL-1β double tran...

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Udgivet i:Oncotarget
Main Authors: Kong, Jianping, Sai, Hong, Crissey, Mary Ann S., Jhala, Nirag, Falk, Gary W., Ginsberg, Gregory G., Abrams, Julian A., Nakagawa, Hiroshi, Wang, Kenneth, Rustgi, Anil K., Wang, Timothy C., Lynch, John P.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741744/
https://ncbi.nlm.nih.gov/pubmed/26460825
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