Autophagy levels are elevated in Barrett’s esophagus and promote cell survival from acid and oxidative stress

Autophagy is a highly conserved mechanism that is activated during cellular stress. We hypothesized that autophagy may be induced by acid reflux, which causes injury and inflammation, and therefore contributes to the pathogenesis of Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC). Curre...

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Podrobná bibliografie
Vydáno v:Mol Carcinog
Hlavní autoři: Kong, Jianping, Whelan, Kelly A., Laczkó, Dorottya, Dang, Brendan, Monroig, Angeliz Caro, Soroush, Ali, Falcone, John, Amaravadi, Ravi K., Rustgi, Anil K., Ginsberg, Gregory G, Falk, Gary W, Nakagawa, Hiroshi, Lynch, John P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794420/
https://ncbi.nlm.nih.gov/pubmed/26373456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22406
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