Normal mammary epithelial cells promote carcinoma basement membrane invasion by inducing microtubule-rich protrusions

Recent work suggests that the dissemination of tumor cells may occur in parallel with, and even preceed, tumor growth. The mechanism for this early invasion is largely unknown. Here, we find that mammary epithelial cells (MECs) induce neighboring breast carcinoma cells (BCCs) to cross the basement m...

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Опубликовано в: :Oncotarget
Главные авторы: Lee, Meng-Horng, Wu, Pei-Hsun, Gilkes, Daniele, Aifuwa, Ivie, Wirtz, Denis
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2015
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741718/
https://ncbi.nlm.nih.gov/pubmed/26334095
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