Normal mammary epithelial cells promote carcinoma basement membrane invasion by inducing microtubule-rich protrusions

Recent work suggests that the dissemination of tumor cells may occur in parallel with, and even preceed, tumor growth. The mechanism for this early invasion is largely unknown. Here, we find that mammary epithelial cells (MECs) induce neighboring breast carcinoma cells (BCCs) to cross the basement m...

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Udgivet i:Oncotarget
Main Authors: Lee, Meng-Horng, Wu, Pei-Hsun, Gilkes, Daniele, Aifuwa, Ivie, Wirtz, Denis
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741718/
https://ncbi.nlm.nih.gov/pubmed/26334095
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