Colorectal cancer-related mutant KRAS alleles function as positive regulators of autophagy

The recent interest to modulate autophagy in cancer therapy has been hampered by the dual roles of this conserved catabolic process in cancer, highlighting the need for tailored approaches. Since RAS isoforms have been implicated in autophagy regulation and mutation of the KRAS oncogene is highly fr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Alves, Sara, Castro, Lisandra, Fernandes, Maria Sofia, Francisco, Rita, Castro, Paula, Priault, Muriel, Chaves, Susana Rodrigues, Moyer, Mary Pat, Oliveira, Carla, Seruca, Raquel, Côrte-Real, Manuela, Sousa, Maria João, Preto, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741568/
https://ncbi.nlm.nih.gov/pubmed/26418750
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