Adiponectin Upregulates MiR-133a in Cardiac Hypertrophy through AMPK Activation and Reduced ERK1/2 Phosphorylation

Adiponectin and miR-133a are key regulators in cardiac hypertrophy. However, whether APN has a potential effect on miR-133a remains unclear. In this study, we aimed to investigate whether APN could regulate miR-133a expression in Angiotensin II (Ang II) induced cardiac hypertrophy in vivo and in vit...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Li, Ying, Cai, Xiaojun, Guan, Yuqing, Wang, Lei, Wang, Shuya, Li, Yueyan, Fu, Ying, Gao, Xiaoyuan, Su, Guohai
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741527/
https://ncbi.nlm.nih.gov/pubmed/26845040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148482
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