CXCL3 contributes to CD133(+) CSCs maintenance and forms a positive feedback regulation loop with CD133 in HCC via Erk1/2 phosphorylation

Although the chemotactic cytokine CXCL3 is thought to play an important role in tumor initiation and invasion, little is known about its function in hepatocellular carcinoma (HCC). In our previous study, we found that Ikaros inhibited CD133 expression via the MAPK pathway in HCC. Here, we showed tha...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Zhang, Lin, Zhang, Lixing, Li, Hong, Ge, Chao, Zhao, Fangyu, Tian, Hua, Chen, Taoyang, Jiang, Guoping, Xie, Haiyang, Cui, Ying, Yao, Ming, Li, Jinjun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891684/
https://ncbi.nlm.nih.gov/pubmed/27255419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27426
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