A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer

The homeobox A (HOXA) region of protein-coding genes impacts female reproductive system embryogenesis and ovarian carcinogenesis. The 5-prime end of HOXA includes three long non-coding RNAs (lncRNAs) (HOXA10-AS, HOXA11-AS, and HOTTIP) that are underexplored in epithelial ovarian cancer (EOC). We eva...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Richards, Edward J., Permuth-Wey, Jennifer, Li, Yajuan, Chen, Y. Ann, Coppola, Domenico, Reid, Brett M., Lin, Hui-Yi, Teer, Jamie K., Berchuck, Andrew, Birrer, Michael J., Lawrenson, Kate, Monteiro, Alvaro N.A., Schildkraut, Joellen M., Goode, Ellen L., Gayther, Simon A., Sellers, Thomas A., Cheng, Jin Q.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741487/
https://ncbi.nlm.nih.gov/pubmed/26430965
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