HOXA13 in etiology and oncogenic potential of Barrett’s esophagus

Barrett’s esophagus in gastrointestinal reflux patients constitutes a columnar epithelium with distal characteristics, prone to progress to esophageal adenocarcinoma. HOX genes are known mediators of position-dependent morphology. Here we show HOX collinearity in the adult gut while Barrett’s esopha...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Janmaat, Vincent T., Nesteruk, Kateryna, Spaander, Manon C. W., Verhaar, Auke P., Yu, Bingting, Silva, Rodrigo A., Phillips, Wayne A., Magierowski, Marcin, van de Winkel, Anouk, Stadler, H. Scott, Sandoval-Guzmán, Tatiana, van der Laan, Luc J. W., Kuipers, Ernst J., Smits, Ron, Bruno, Marco J., Fuhler, Gwenny M., Clemons, Nicholas J., Peppelenbosch, Maikel P.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184780/
https://ncbi.nlm.nih.gov/pubmed/34099670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23641-8
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