Next generation sequencing in synovial sarcoma reveals novel gene mutations

Over 95% of all synovial sarcomas (SS) share a unique translocation, t(X;18), however, they show heterogeneous clinical behavior. We analyzed multiple SS to reveal additional genetic alterations besides the translocation. Twenty-six SS from 22 patients were sequenced for 409 cancer-related genes usi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Vlenterie, Myrella, Hillebrandt-Roeffen, Melissa H.S., Flucke, Uta E., Groenen, Patricia J.T.A., Tops, Bastiaan B.J., Kamping, Eveline J., Pfundt, Rolph, de Bruijn, Diederik R.H., van Kessel, Ad H.M. Geurts, van Krieken, Han J.H.J.M., van der Graaf, Winette T.A., Versleijen-Jonkers, Yvonne M.H.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741482/
https://ncbi.nlm.nih.gov/pubmed/26415226
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