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Next generation sequencing in synovial sarcoma reveals novel gene mutations

Over 95% of all synovial sarcomas (SS) share a unique translocation, t(X;18), however, they show heterogeneous clinical behavior. We analyzed multiple SS to reveal additional genetic alterations besides the translocation. Twenty-six SS from 22 patients were sequenced for 409 cancer-related genes usi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Vlenterie, Myrella, Hillebrandt-Roeffen, Melissa H.S., Flucke, Uta E., Groenen, Patricia J.T.A., Tops, Bastiaan B.J., Kamping, Eveline J., Pfundt, Rolph, de Bruijn, Diederik R.H., van Kessel, Ad H.M. Geurts, van Krieken, Han J.H.J.M., van der Graaf, Winette T.A., Versleijen-Jonkers, Yvonne M.H.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741482/
https://ncbi.nlm.nih.gov/pubmed/26415226
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