Next generation sequencing in synovial sarcoma reveals novel gene mutations

Over 95% of all synovial sarcomas (SS) share a unique translocation, t(X;18), however, they show heterogeneous clinical behavior. We analyzed multiple SS to reveal additional genetic alterations besides the translocation. Twenty-six SS from 22 patients were sequenced for 409 cancer-related genes usi...

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Vydáno v:Oncotarget
Hlavní autoři: Vlenterie, Myrella, Hillebrandt-Roeffen, Melissa H.S., Flucke, Uta E., Groenen, Patricia J.T.A., Tops, Bastiaan B.J., Kamping, Eveline J., Pfundt, Rolph, de Bruijn, Diederik R.H., van Kessel, Ad H.M. Geurts, van Krieken, Han J.H.J.M., van der Graaf, Winette T.A., Versleijen-Jonkers, Yvonne M.H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741482/
https://ncbi.nlm.nih.gov/pubmed/26415226
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