Cetuximab promotes epithelial to mesenchymal transition and cancer associated fibroblasts in patients with head and neck cancer

PURPOSE: To investigate if cetuximab induces epithelial to mesenchymal transition (EMT) and activation of cancer associated fibroblast (CAF) in the tumors of patients with squamous cell carcinoma of the head and neck (SCCHN). METHODS: Cetuximab was administered for two weeks prior to surgery to 20 t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Schmitz, Sandra, Bindea, Gabriela, Albu, Roxana Irina, Mlecnik, Bernhard, Machiels, Jean-Pascal
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741452/
https://ncbi.nlm.nih.gov/pubmed/26437222
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