Cetuximab promotes epithelial to mesenchymal transition and cancer associated fibroblasts in patients with head and neck cancer

PURPOSE: To investigate if cetuximab induces epithelial to mesenchymal transition (EMT) and activation of cancer associated fibroblast (CAF) in the tumors of patients with squamous cell carcinoma of the head and neck (SCCHN). METHODS: Cetuximab was administered for two weeks prior to surgery to 20 t...

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Publicado en:Oncotarget
Autores principales: Schmitz, Sandra, Bindea, Gabriela, Albu, Roxana Irina, Mlecnik, Bernhard, Machiels, Jean-Pascal
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741452/
https://ncbi.nlm.nih.gov/pubmed/26437222
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