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Cetuximab promotes epithelial to mesenchymal transition and cancer associated fibroblasts in patients with head and neck cancer

PURPOSE: To investigate if cetuximab induces epithelial to mesenchymal transition (EMT) and activation of cancer associated fibroblast (CAF) in the tumors of patients with squamous cell carcinoma of the head and neck (SCCHN). METHODS: Cetuximab was administered for two weeks prior to surgery to 20 t...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Schmitz, Sandra, Bindea, Gabriela, Albu, Roxana Irina, Mlecnik, Bernhard, Machiels, Jean-Pascal
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741452/
https://ncbi.nlm.nih.gov/pubmed/26437222
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