Cetuximab promotes epithelial to mesenchymal transition and cancer associated fibroblasts in patients with head and neck cancer

PURPOSE: To investigate if cetuximab induces epithelial to mesenchymal transition (EMT) and activation of cancer associated fibroblast (CAF) in the tumors of patients with squamous cell carcinoma of the head and neck (SCCHN). METHODS: Cetuximab was administered for two weeks prior to surgery to 20 t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Schmitz, Sandra, Bindea, Gabriela, Albu, Roxana Irina, Mlecnik, Bernhard, Machiels, Jean-Pascal
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741452/
https://ncbi.nlm.nih.gov/pubmed/26437222
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