Macromolecular crowding develops heterogeneous environments of gene expression in picoliter droplets

Understanding the dynamics of complex enzymatic reactions in highly crowded small volumes is crucial for the development of synthetic minimal cells. Compartmentalised biochemical reactions in cell-sized containers exhibit a degree of randomness due to the small number of molecules involved. However,...

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Bibliographic Details
Published in:Nat Nanotechnol
Main Authors: Hansen, Maike M. K., Meijer, Lenny H. H., Spruijt, Evan, Maas, Roel J. M., Roquelles, Marta Ventosa, Groen, Joost, Heus, Hans A., Huck, Wilhelm T. S.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740931/
https://ncbi.nlm.nih.gov/pubmed/26501750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nnano.2015.243
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