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Macromolecular crowding develops heterogeneous environments of gene expression in picoliter droplets

Understanding the dynamics of complex enzymatic reactions in highly crowded small volumes is crucial for the development of synthetic minimal cells. Compartmentalised biochemical reactions in cell-sized containers exhibit a degree of randomness due to the small number of molecules involved. However,...

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Pubblicato in:Nat Nanotechnol
Autori principali: Hansen, Maike M. K., Meijer, Lenny H. H., Spruijt, Evan, Maas, Roel J. M., Roquelles, Marta Ventosa, Groen, Joost, Heus, Hans A., Huck, Wilhelm T. S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740931/
https://ncbi.nlm.nih.gov/pubmed/26501750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nnano.2015.243
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