Enterohemorrhagic Escherichia coli Reduces Mucus and Intermicrovillar Bridges in Human Stem Cell-Derived Colonoids

BACKGROUND & AIMS: Enterohemorrhagic Escherichia coli (EHEC) causes over 70,000 episodes of foodborne diarrhea annually in the United States. The early sequence of events that precede life-threatening hemorrhagic colitis and hemolytic uremic syndrome is not fully understood due to the initial as...

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Udgivet i:Cell Mol Gastroenterol Hepatol
Main Authors: In, Julie, Foulke-Abel, Jennifer, Zachos, Nicholas C., Hansen, Anne-Marie, Kaper, James B., Bernstein, Harris D., Halushka, Marc, Blutt, Sarah, Estes, Mary K., Donowitz, Mark, Kovbasnjuk, Olga
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740923/
https://ncbi.nlm.nih.gov/pubmed/26855967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2015.10.001
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