Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology

Identification of Lgr5 as the intestinal stem cell marker as well as the growth factors necessary to replicate adult intestinal stem cell division has led to the establishment of the methods to generate “indefinite” ex vivo primary intestinal epithelial cultures, termed “mini-intestines.” Primary cu...

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Vydáno v:J Biol Chem
Hlavní autoři: Zachos, Nicholas C., Kovbasnjuk, Olga, Foulke-Abel, Jennifer, In, Julie, Blutt, Sarah E., de Jonge, Hugo R., Estes, Mary K., Donowitz, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759158/
https://ncbi.nlm.nih.gov/pubmed/26677228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.635995
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