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Human Enteroids/Colonoids and Intestinal Organoids Functionally Recapitulate Normal Intestinal Physiology and Pathophysiology

Identification of Lgr5 as the intestinal stem cell marker as well as the growth factors necessary to replicate adult intestinal stem cell division has led to the establishment of the methods to generate “indefinite” ex vivo primary intestinal epithelial cultures, termed “mini-intestines.” Primary cu...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Zachos, Nicholas C., Kovbasnjuk, Olga, Foulke-Abel, Jennifer, In, Julie, Blutt, Sarah E., de Jonge, Hugo R., Estes, Mary K., Donowitz, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759158/
https://ncbi.nlm.nih.gov/pubmed/26677228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.635995
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