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The influence of a caveolin-1 mutant on the function of P-glycoprotein

The genetic heterogeneity in cancer cells has an increased chance in the acquisition of new mutant such as drug-resistant phenotype in cancer cells. The phenotype of drug resistance in cancer cells could be evaluated by the number or function of drug transporters on cell membranes, which would lead...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, Chih-Yuan, Lai, Ting-Yu, Tsai, Meng-Kun, Ou-Yang, Pu, Tsai, Ching-Yi, Wu, Shu-Wei, Hsu, Li-Chung, Chen, Jin-Shing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740904/
https://ncbi.nlm.nih.gov/pubmed/26843476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20486
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