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Activation of the AMP-activated Protein Kinase – p38 MAP Kinase Pathway Mediates Apoptosis induced by Conjugated Linoleic Acid in p53-Mutant Mouse Mammary Tumor Cells
Conjugated linoleic acid (CLA) inhibits tumorigenesis and tumor growth in most model systems, an effect mediated in part by its pro-apoptotic activity. We previously showed that trans-10,cis-12 CLA induced apoptosis of p53-mutant TM4t mouse mammary tumor cells through both mitochondrial and endoplas...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838459/ https://ncbi.nlm.nih.gov/pubmed/19932174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.11.011 |
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