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Conjugated linoleic acid induces apoptosis of murine mammary tumor cells via Bcl-2 loss
Conjugated linoleic acid (CLA) is a powerful anticancer agent in a number of tumor model systems; however, its precise mechanism of action remains elusive. Here, we report that t10,c12 CLA, a component of synthetic CLA supplements, induced apoptosis and G(1) arrest of p53 mutant TM4t murine mammary...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1992442/ https://ncbi.nlm.nih.gov/pubmed/17400188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.03.096 |
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